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Fer-1 fails to enhance the p53/SLC7A11/GPX4 pathway but improves the Nrf2/ferroptosis inhibitory protein 1 pathway, boosting resistance to LPO (You et al., 2023)

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171 Additionally, refluxed acid and bile help stabilize hypoxia-inducible factor-2 (a key transcription factor that plays a critical role in cellular and systemic responses to hypoxia) in esophageal epithelial cells

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Konopleva M, Samudio I, Tsao T, Konblau SM, Y-X S, McQueen T, Contractor R, Sporn MB, Meyer CJ, Huff W, Safe SH, Kantarjian H, Andreeff M

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